Cirrhosis is a general condition that is the end result of liver injury and is often seen as chronic.

It can lead to nodule formation and fibrosis of the Liver.

Serious medical condition that is generally unable to reverse.

Has several different causes that lead to Cirrhosis

One of the top leading causes of death in the US about 1-2% of all deaths.

Divided into micronodular, macronodular, and mixed forms.

Causes the liver to loose its function such as:  metabolism of nutrients, bile production, and detoxification of blood along with other functions.

 

3 Main Clinical features:

1.)  Hepatic cell dysfunction

2.)  Portosystemic shunting

3.)  Portal hypertension

 

Causes of Cirrhosis:

–  Alcoholic liver disease

–  Hepatitis C

–  Hepatitis B

–  Autoimmune Hepatitis

–  Primary and Secondary Bilary Cirrhosis

–  Primary Sclerosing Cholangitis

–  Alpha 1-Antitypsin Deficiency

–  Wilson’s Disease
–  Hemochromatosis

–  Drug induced liver disease

–  Many others

 

Symptoms:

–  Weakness

–  Fatigue

–  Weight loss

–  Nausea

–  Abdominal pain

–  Enlarged liver (70%)

–  Enlarged spleen fever

–  Acities

–  and others.

 

Varices are common with portal hypertension

 

Diagnosis

Doppler studies

CT

MRI

Blood work

liver biopsy may be appropriate.

 

Treatment:

–  Stop consuming alcohol

–  Diet change

–  Loss of weight

–  Diuretic: Spironolactone

–  Paracentesis

–  Transjugular intrahepatic portosystemic shunt (TIPS) for variceal bleeding that has no improvement with tradition means (endoscopic band ligation or sclerotherapy)

–  Antibiotics when necessary

–  Liver Transplant

VN:F [1.9.22_1171]
Rating: 0.0/10 (0 votes cast)
VN:F [1.9.22_1171]
Rating: 0 (from 0 votes)