Thiazide
   ·   Hydrochlorothiazide
   ·   Metolazone
   ·   Chlorthilidone


– Block sodium respoorption in cortical diluting segment – at terminal point of loop of Henle.
– Become ineffective when GFR goes below 30-40 mL/min

Loop Diuretics
   ·   Furosemide
   ·   Bumetanide
   ·   Torsemide


– Inhibit chloride reabsorption in ascending limb of the loop of Henle

Potassium-Sparing agents
   ·   Spironolactone
   ·   Triamterene
   ·   Eplerenone
   ·   Amiloride

– Can be used in combo with Loop diuretics and Thiazides
Triameterene and Amiloride work in distual tubule to limitpotassium secretion
Spironolactone inhibits aldosterone – which is often elevated in CHF
Eplerenone is used for post MI cases

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