A disease that involves the lungs, causing hemorrhage, and kidney destruction

Rather rare disease

Often involved as an autoimmune disease

Is when the immune system attacks the “Goodpasture antigen” causing the destruction

This antigen is often found in the kidney and lungs

Occurs more often in men in their 30s and 40s

Lungs
   -   damage can be severe
   -   may occur quickly
   -   may become anemic

Kidney
   -   may cause a form of nephritis
   -   may ocucur quickly
   -   acute renal failure may result

Symptoms
   –    Coughing of blood   [hemoptysis]
   -    Pain with breathing
   -    Cough
   -    Blood in urine    [hematuria]
   -    Edema
   -    Fatigue
   -    Nausea
   -    and others

Kidney biopsy is helpful
Blood test identifying anti-GBM is useful

Treatment

- Medication
•         Corticosteroids
•         Cyclophosphamide
•         Antibiotics in some individuals

- Plasmaphersis
- Kidney transplant is rare cases