osteoporosis

Occurs when a decrease in bone density occurs within an individual

A large increased risk and propensity for fractures exhists in those with osteoporosis

The majority of women who develop osteoporosis do so after menopause.

But in can occur in any age and in both men and women

Is considered preventable with medication, life style changes and increase exercises in some cases

All women over 65 should be screened for osteoporosis

Below 65 should be screened when they have assoicated risk factors or a unexpected fracture

Between 65 and 80 are when men are often screened

Symptoms

   -    No specific symptoms are seen
   -    Often fractures are first findings
   -    Fractures can occur in vertebral column, ribs, hips, and wrist
   -    Compression fractures suddenly occur causing pain
   -    Unexpected falls

Risk factors:

   -    Vitamin D deficiency
   -    Smoking
   -    Excess
   -    Alcohol
   -    Physical inactivity
   -    Underweight
   -    Soft drinks

Causes:

   -    Endocrine disorders
   -    Malnutrition
   -    Immobilization
   -    Space Flight
   -    Rheumatoid Arthritis
   -    Medications
   -    and many others

DEXA or DXA scan to evaluate bone density

Diagnostic criteria by “World Health Organization”

T-score of greater then          - 1.0                    -       Normal
T-score of between                - 1.0 and – 2.5    -       Low bone mass = osteopenia
T-score of less then               - 2.5 or below     -       Osteoporosis

Treatment

Bisphosphonates

.         Sodium Alendronate    [Fosamax]
.         Risedronate    [Actonel]
.         Ibandronate    [Boniva]
.         Zoledronic Acid    [Zoledronate, Zometa]

.         Teriparatide     [Forteo] -

.         Strontium Ranelate  -  Dual action bone agents

.         Estrogen replacement therapy
                -     not always recommended for each person

.         Testosterone treatment in men

Calcium supplement

Vitamin D

Exercise
    -     Aerobics
    -     Resistance
    -     Weight bearing
    -     Walking
    -     others

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