ProtonpumpProton Pump Inhibitors is a group of drugs that affects and decreases the amount of acid in the Stomach.

They are newer then the H2-Receptor Antagonists

Are used quite often throughout the world and are some of the medication that are most purchased.

Uses include:

-    Gastroesophageal Reflux Disease (Gerd)
-    Dyspepsia
-    Heartburn
-    Peptic Ulcers
-    Barrett’s esophagus
-    Zollinger-Ellison syndrome

Types:

.         Omeprazole   [Prilosec]
.         Lansoprazole   [Prevacid]
.         Esomeprazole   [Nexium]
.         Pantoprazole   [Protonix]
.         Rabeprazole   [Aciphex]
.         Dexlansoprazole   [Kapidex]

Method of Action

-    Block a H+/K+ ATPase pump system also called the gastric proton pump

-    Occurs in the stomach at the perietal cell

proton prilosec_10620_4_big_Adverse Effects

-    Nausea
-    Vomiting
-    Headache
-    Fatigue
-    Rash
-    Itching
-    Abdominal pain
-    Erythema multiforme
-    Pancreatitis
-    Stevens Johnson Syndrome
-    others

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