Is a group of drugs that affects and decreases tha amount of acid in the stomach

They are newer then the H2-receptor antagonists

Are used quite often throughout the world.

Uses include:

   -    Gastroesophageal-Reflux-Disease-(Gerd)
   -    Dyspepsia
   -    Heartburn
   -    Peptic Ulcers
   -    Barrett’s esophagus
   -    Zollinger-Ellison syndrome

Types:
.         Omeprazole   [Prilosec]
.         Lansoprazole   [Prevacid]
.         Esomeprazole   [Nexium]
.         Pantoprazole   [Protonix]
.         Rabeprazole   [Aciphex]
.         Dexlansoprazole   [Kapidex]

Method of Action

   -    Block a H+/K+ ATPase pump system also called the gastric proton pump
   -    Occurs in the stomach at the perietal cell

Adverse Effects

   -    Nausea
   -    Vomiting
   -    Headache
   -    Fatigue
   -    Rash
   -    Itching
   -    Abdominal pain
   -    Erythema multiforme
   -    Pancreatitis
   -    Stevens Johnson Syndrome
   -    others