It is seen in about 2 per every 100,000 individuals
Some cause agents are: Hepatitis A, Epstein-Barr infection, measles, and drug or toxin agents.
Typically seen young women but can be seen in either sex and at any age. [Almost 70% of the time]
Can be a very quick initial onset.
- Multiple spider nevi
- Enlarged liver
- Increased liver enzymes
Type I – SMA and/or ANA
Type II – Anti-LKMI â€“ typically children 2-14 years of age
Type III – Anti SLA/LP
- Prednisone with or without Azathioprine – 80% response rate
- Mercaptopurine instead of Azathioprine in some cases
If failure other medication options include
Liver transplant may be required if treatment failure
Reoccurrences can occur in 40% of transplanted livers