Azathioprine
Azathioprine is a medication in the class of drug that are used as an immunosuppressant that is often used in autoimmune diseases.
A pro-drug that metabolizes into other compounds that are effective in treatment.
Becomes 6-Mercaptopurine and 6-Thioinosinic acid
This medication is also called [Imuran and Azasan]
Most Common Uses:
1.) Crohn’s Disease
2.) Ulcerative Colitis
3.) Multiple Sclerosis
4.) Rheumatoid Arthritis
Method of Action
– Action works as a Purine synthesis Inhibitor
– Stops or slows some cellular action
– Works specifically with DNA and RNA
Side Effects
– Nausea
– Vomiting
– Rash
– Decreases bone marrow growth
– Hair loss
– other
Use during Pregnancy
Can be used on rare occasions during pregnancy when the benefit outweighs the risk