Birth Control advancements are pushing towards an oral pill developed strictly for men. This controversial research calls into question the effectiveness and risks for men. For years, women have asked why they should be the only ones responsible for taking a bill to prevent pregnancy.
In addition, questionnaires have shown an increased desire for men to take an oral contraceptive.
But it seems, as far as research shows, a successful and effective male oral contraceptive has been harder to finalize.
In a statement, Jillian Kyzer said, “At certain doses, it (works). But at those doses, it doesn’t work for up to 20% of men, and it can cause side effects, including weight gain and a decrease in ‘good’ cholesterol.” Kyzer is a graduate student at the University of Minnesota who has been working on a male contraceptive pill.
Lead researcher Gunda I. Georg, PhD, of the University of Minnesota College of Pharmacy, and his colleagues recently presented their findings at the 251st National Meeting & Exposition of the American Chemical Society (ACS) in San Diego, CA.
Some of the studies have investigated the male hormone testosterone as a possible basis for such a drug; a huge side affect has been infertility at higher doses.
Other compounds have been assessed as a male contraceptive pill, but Georg and her team note there are a number of barriers that need to be overcome before such a drug can reach the market.
“The pill would need to be soluble – allowing it to be taken orally – and it would need to work quite quickly, without affecting a man’s sex drive.”
There are some pharmaceutical companies that have reached the experimental stages. Improvements and advancements still need to be seen during research that includes selectivity and not a broad shotgun approach, improved effectiveness, and decreased side effects.
“Even if just 5-10% of men used this (an oral contraceptive), it would limit population growth,” says Ilpo Huhtaniemi, emeritus professor of Reproductive Endocrinology at Imperial College London.
In a study in Mice Published in October 2015, Haruhiko Miyata and colleagues at Osaka University in Japan discovered a protein, called Calcineuron.
This protein may be crucial in helping sperm swim and break through the membrane of a female egg in order to fertilize it. When the genes behind this protein were blocked, the mice became infertile.
Pharmaceutical companies have been trying different areas of research for several years with varied results.
Areas that have been studied or are currently being studied include:
- Controlling sperm production
- Targeting testosterone productions
- Preventing sperm fertilizing with egg
- Decreased sperm motility
- Prevention of ejaculation
Often these different areas will fall into two categories.
Types of Research
1.) Hormonal Contraceptive
2.) Non-Hormonal Contraceptives
Sperm is created in testicles daily – this is triggered by the hormone testosterone. Therefore, the goal is to temporarily block this process – not allowing the production of healthy sperm cells.
The problem is that when this happens and the overall level of testosterone decreases – this causes other side effects including depression, loss of sexual desire, and others.
A possible solution may be the the process of giving men a synthetic version of testosterone. This has been somewhat successful in the testing phases. One problem, is that some men, despite the testosterone changes – still produce enough sperm to cause a pregnancy. The reason is still unknown. Further studies are looking at different combinations of synthetic testosterone and Progesterone.
Many of the studies surround this area deal with the Vas Deferens. This is a tube the sperm passes through on the way to the penis. The vas deferens is cut during a vasectomy.
RISUG is a technique called Reversible Inhibition of Sperm Under Guidance. A chemical (non-toxic) is injected into the vas deferens. This chemical reacts and blocks the process. It kills the sperm it comes in contact with.
The chemical stays in place until the man wants to have children, then it can be washed or flushed away. Long term effectiveness and safety still needs to be researched.
Other research is looking into the Epididymis. This is a coiled tube behind the testicles where sperm matures. Thus far, research hasn’t been very successful.
Other Male Contraceptive Options:
Some other options are more and less effective than others.
Oral Contraceptive for Women
The pill for women went onto the marker in the 1960’s. About 20% of women are currently taking contraceptives or have done so within the last 3 months. The primary age of use is between 15 and 45.
Women’s Health is advancing rapidly and is a very important area of study.
Typically oral contraceptives do not have side effects on libido.
While there are a number of birth control pills available for women, they are not a suitable option for all couples.
Georg says: “It would be wonderful to provide couples with a safe alternative because some women cannot take birth control pills.”
Share your thoughts
Do you think that male birth control pills present a positive potential change in relationships, sex and reproductive health?
For many people, coffee is a food group all on its own. It is taken hot in the morning, cold in the afternoon, and again just before bedtime. It is likely the world’s favorite hot beverage that allows millions of people a reason to get out of bed and a helping hand to get through the day.
Research recently published in the International Journal of Sport Nutrition and Exercise Metabolism suggests the coffee can help power through a difficult workout.
Now ingesting caffeine during an endurance work out isn’t anything new. But the use of coffee has previously been frowned upon. Belief that the effectiveness of coffee would be poor. Researchers conducted a meta-analysis review to evaluate how coffee impacts endurance performance both prior to endurance and during.
This study recently published was intended to look at a few different things:
1.) The Effects of Coffee on taken prior to an Endurance Performance
2.) The Effects of Coffee during exertion during an Endurance Performance
3.) Taking information gathered and make available for athletes to make an Informed Decision
Significant improvement was seen in over half of the participants when coffee was given more than 45 minutes before a workout.
The study also showed that around 50% of those involved in Endurance Performance required less exertion to perform.
The results describe a moderate amount of evidence supporting the use of coffee to improve endurance cycling and running and that it may be a safe alternative to anhydrous caffeine.
“There’s a perception that coffee won’t give you the same benefits as pure caffeine. New research could mean that athletes could have a cup of coffee versus taking a pill.” Simon Higgins, lead author said. He added, “This is helpful for athletes because coffee is a naturally occurring compound…“
During the study coffee was used for exercises of cycling and/or running. Approximately 3-9 milligrams of caffeine per kilogram of body weight increased endurance over 20 percent. This is about 2-5 cups of coffee.
Medical News Today reported that the national average of coffee is more that 25 oz per day with approximately 10% of drinkers – consuming more than 1,000 mg of coffee daily.
Caffeine is widely considered as the most popular psychoactive substance among people of all age groups and cultural backgrounds.
But thus far, in college racing, caffeine is an illegal substance. The NCAA has stated that urinary caffeine levels above 15 μg/ml could result in a ban. This is over 15 caffeinated soft drinks. But this has been seen before.
The World Anti-Doping Agency currently doesn’t classify caffeine as a prohibited substance.
An abstract of the study is available here.
Ebola is a serious medical condition that is the result of the Ebola Virus (EBV). It is part of a family of viruses known as ebolavirus. It is largely known to cause bleeding both internally (inside the body) and externally. It can also be classified as a virus that causes Hemorrhagic Fever.
One of the many causes for concern, is that this condition has a very high death rate – also known as mortality rate.
Symptoms begin as soon as a few days, but they can start almost three weeks after contracting the virus. The primary symptoms include fever, sore throat, headaches, muscle aches, and fatigue.
Abdominal pain, nausea and vomiting, along with diarrhea soon follow behind.
Unfortunately, these set of symptoms could describe many conditions and several other virus including the Influenza Virus, gastrointestinal viruses, and more. Rash is seen in about 50% of the cases.
As the symptoms progress – decreased functioning of the Kidneys and Liver are seen. Bleeding or Hemorrhaging starts around this time. Bleeding can occur from the mouth, nose, Stomach, Vagina, gums. Bloody eyes and bloody vomit can be seen.
Transmission occurs initially through animals that are infected such as: fruit bats or monkeys and even pigs. Human transmission occurs when a human comes into contact with the blood of these animals.
Once human infection occurs, the disease spreads through contact of blood or body fluids. It is believed that male survivors may be able to transmit the disease via semen for up to two months post infection.
Transmission can occur even after death and from medical instruments that were involved in the treatment of someone with this condition. Airborne transmission has not been seen and is not believed to be a manner of transmission.
Prevention and Treatment are key. Avoid blood and body fluids of those suspected to have come into contact with the Ebola Virus. Properly cooking meat and wearing protective clothing when handling meat.
Treatment is mostly for the symptoms – therefore treat dehydration, fever, and other symptoms as soon as possible.
There are two medications that are being tested in the United States. This is considered a medically approved circumstance and the use of these medications despite not being approved by the FDA. The two drugs are ZMapp and TKM-Ebola.
Club Foot is a deformity of the foot and ankle that can completely affect the movement and function of the foot and/or ankle. There are three main types of deformities that can be seen. The actual cause of club foot is debatable.
Some argue that no single cause exists for club foot. As you will read, there is quite a bit of controversy in the cause of this condition.
Often the cause of this diagnosis is called idiopathic – or unknown. This doesn’t sit well with everyone, in fact, I recently received an angry email (she gave permission to make reference) regarding a doctor’s visit she had where the cause was classified as unknown.
At the same time, there are certain syndromes or birth defects that see a higher propensity of having a club foot. Therefore, club foot can happen on its own or because of other genetic or other conditions.
Essentially, club foot is a congenital deformity that happens in 1 out of every 1,000 births. It is seen twice as often in men than in women. It can be seen in screening during the 20th week ultrasound. At that time, the development is advanced enough to get a good look.
Screening is somewhat controversial. Many doctors, because this condition can be associated with other birth defects, screening becomes that much more important.
If only the birth defect of club foot is seen, it is called isolated. But if club foot plus another congenital deformity is seen – it becomes complex.
Other birth defects that can be associated with club foot include spina bifida, Edwards syndrome, Growth arrests, and others.
A large cause is not by congenital disorders changes but rather the position of the baby when inside the womb of the mother. Though this topic is another point of controversy. Others believe that this has no bearing on the presence of club foot.Â In these cases, the cause is often unknown.
Other risk factors that are considered environmental factors or causes include sex, mother smoking (20 times more likely), family history, decrease in amniotic fluid, illicit drug use, and infections during pregnancy.
Some studies have shown that there’s a 2.5% chance that the next sibling born in a family after one with a club foot will also have this condition. If its a girl who has a club foot, there’s a 6.5 percent chance that her next-born sibling will also have a club foot. This is quite interesting.
Learn more about additional risk factors, treatment, different types, and joints affected at the following link – here
As parents, it has been beaten into our minds that there are foods that shouldn’t be given too early in our baby’s lives.
Be it for reasons such as food allergy, ability to consume, or another reason such as family folklore. It is certain that every parent struggles when to give solid foods, certain foods, and liquids such as milk and water. There are foods such as whole milk, peanut butter, eggs, fish, and more that we’ve been told to wait because of food allergies. Usually we are waiting until our children reach at least one year until we even consider giving these foods.
Could the time to give these food items actually be sooner than previous recommendations?
Back in 2000 – The American Academy of Pediatrics (AAP) suggested that Milk was to be given after 1 year of age. Eggs were to be given after 2 years of age. Peanuts and Fish weren’t to be given before age 3.
In 2008 and 20111 – The recommendations were changed by the American Academy of Pediatrics (AAP) – they indicated that no data was present to continue with their previous recommendations. But that had been 8 years of Parents, Pediatricians, and other providers believing and following the recommendations. It has been hard, even from a provider’s standpoint, to change those recommendations given to parents when the question was asked.
Recently, this topic has been looked at by the American Academy of Allergy, Asthma & Immunology. Further evaluation on when was the right time to give foods is a highly debated topic. The findings from the American Academy of Allergy, Asthma & Immunology suggest that milk, eggs, fish, and peanut butter can be given safely as early as 4 – 6 months of age. In addition, it is believed that this may actually prevent a child from developing allergies to these items in the future.
Dr. David Fleisher, a lead author and an Associate Professor of Pediatrics at National Jewish Health at the University of Colorado said, “The key point is that there is no reason why you can’t introduce them early for most children. Children with moderate to severe eczema that is difficult to treat or ones who have already been diagnosed with a [different type of] food allergy are at higher risk. So you may want to wait until they are tested before introducing peanuts or eggs.”
Medical providers, Physicians, and Specialists should advise parents to introduced plain floods such as fruits, vegetables, cereal before offering the other choices. It is not recommended that milk, eggs, fish, or peanuts be the first solid food a baby receives.
Reactions to food allergens can be highly varied.
This is important to understand. There is an entire spectrum of reactions to foods. Some will have very mild symptoms that may not even be noticed. There may be some headaches, itchiness, Inflammation, or other symptoms.
That is a far contrast to a more serious type of reaction that can cause difficulty breathing or wheezing.
Very serious effects can be seen with throat closing and life-threatening anaphylaxis.
Genetic Issues with Allergies
There is obvious a genetic complexity with parents and offspring having allergies. It could be a cousin, grandmother, or sibling. But this is not true in all cases. Caution should be given when family members have food allergies. It doesn’t mean that we shouldn’t give peanuts to our child in those cases, but we need to be cautious and careful.
There are currently no genetic testing that can be done during pregnancy that can help determine if our children will have allergies.
Hope is that this will be a future area where medical advancement and research can be seen.
Common Food Allergies
Food allergies in children is on the rise.
Currently around 1 in 12 or 1 in 15 – In the United States – have food allergies.
Most common food allergy is Peanuts
Milk is second most common followed by Shellfish.
Other foods include nuts, fish, wheat, soy, mushrooms, and others.
Children with food allergy also have higher rates of Asthma, skin complaints (Eczema), and Allergies.
The following are 5 important questions about Intrauterine Device – IUD’s. This type of contraception is used by millions of women. Initial questions are usually easy to find. These questions really help understand what we can expect and it helps answers concerns we might have.
1.) What kinds of IUD or Intrauterine Devices are there?
2 main types.
1.) Non-hormonal Copper IUD (ParaGard)
2.) Hormonal IUD (Mirena)
Copper IUD is a copper wire that wraps around the T shape device.
Hormonal IUD releases a hormone Levonorgestrel. The Copper IUD is good for 10 years while the Hormonal IUD is good for 5 years.
2.) Can an IUD be used during breastfeeding?
Yes. Neither will result in side effects or are harmful to the infant. The quality or quantity of the Breast milk is not affected.
3.) Should I use another form of contraception during the first month of an IUD?
For the copper IUD – It is effective the moment it is placed. In some cases, it can be effective within the first 5 days after intercourse. This would be considered as Emergency Contraceptive and would be more effective than oral pills.
For the Hormonal IUD – Immediately effective if placed within 7 days after you started your period. Otherwise, used alternative contraception for the first 7 days.
4.) Will an IUD affect my period?
Copper IUD – May cause irregular menstrual periods. Your periods might become heavier and last longer than you are used to. Cramping can be seen. Complete absence of a period is unlikely.
Hormonal IUD – Irregular menstrual periods are possible. Decrease in duration and intensity of your period is often seen. You may experience less cramping. Complete absence of a period is likely but doesn’t occur in all cases.
*** Sometimes heavy menstrual periods or very painful menstrual periods are the primary reasons to get a hormonal IUD.
5.) Can I get pregnant while I have an IUD
Yes. Although this rarely happens. It is possible. If you think that you could be, meet with your provider immediately.
They may want to ensure you aren’t having an ectopic pregnancy. Ultrasound, exam, blood work, and other evaluations may occur.
If you have a normal pregnancy you can than choose whether to continue the pregnancy.
If you choose to continue with the pregnancy the IUD will be removed immediately. If you keep the IUD during pregnancy you will risk your health and your baby’s health.
There is a risk of miscarriage when removing the IUD.
If the IUD can’t be removed, you will be monitored closely during pregnancy.
Learn more specifics about the IUD or Intrauterine Device – Here
Take a look at our most recent medical question sent in. It isn’t for everyone – but it’s some useful information.
Our child recent underwent surgery for Pyloric Stenosis. We were shocked by the news that our baby was sick. We are hopeful that this will help. Can you please get out the news.
Pyloric Stenosis is an interesting and well understood condition. It affects boys much more than girls. In fact, it often affects the first born males almost 4 times more than others. I am not sure if that is the case from our email reader. But it something to think about.
When you have your well child check ups – this is something that is often looked for. It “develops” in the first six weeks of life. Sometimes it can be seen in older children, but this is unlikely. The presenting symptoms is often projectile vomiting. Of course, projectile vomiting can happen in several other diseases – but this needs to be considered each time.
An exam will happen and a mass can be felt in the abdomen in most cases. The word “mass” is often never a good sign. In this case, the mass comes from the functional problem of this condition. Stenosis means narrowing and Pyloric often refers to the stomach and means gate. In this case therefore – a narrowing of the gate is occurring. The location is near the end of the stomach and the Small Intestines.
Food enters the stomach and gets broken down. Some digesting of the food happens in the stomach, but more digesting happens in the intestines. In infants with pyloric stenosis – the food can’t pass from the stomach to the intestines and it therefore is vomited back out the mouth. It needs to go somewhere.
A muscle that helps with the closing of the Stomach when empty becomes quite enlarged. This muscle does not allow for the complete opening of the stomach into the intestines. This portion of the intestines is known as the duodenum. AS the muscle thickens – the opening becomes smaller and smaller.
The real concern of this condition is malnutrition and dehydration. As both consequences advance, serious complications can be seen by the infant. Loss of weight, abdominal pain, food hungers, crying can be seen.
The treatment of this condition is Surgery. A 3-4 cm incision used to be the treatment of choice. Now, laproscopy is the preferred treatment. IV fluids will often be given prior to and after surgery. A child may remain in the hospital for 1-2 days – more if a complication is experienced. Recovery is often seen.
The main question about this condition is cause. Functionally – an enlarged muscle is the answer. But, an exact cause is often unknown. Genetics is a likely cause and some see Erythomycin given in the first month of life as another cause possibility. It is believed that a baby is not born with the condition but develops it early in life.
Learn more about Pyloric Stenosis here:
I recently received an email asking about Addison Crisis.
It reads: My sister-in law just was sent to the hospital and came back with a Diagnosis of Addison Disease and was told she had a crisis. What does this mean?
The answer is interesting.
The first thing to understand is about Addison’s Disease:
In this condition, the the Adrenal Gland does not produce enough steroid hormones. (Glucocorticoids as well as mineralocorticoids)
It is a rare condition that affects the Endocrine System. This condition can also be called: Chronic Adrenal Insufficiency. 70-80% of the time, there is an insufficiency of the adrenal hormone called Cortisol.
Often the cause is damage from one’s own Immune System. This can be referred to as Primary Adrenal Insufficiency. Tumors can be seen, but this is a rare cause agent.
**** Addison’s disease is named after Dr. Thomas Addison, the British physician who first described the condition in 1849
Now, onto Addison Crisis!!
It is really called an Addisonian Crisis. This occurs possibly as the result of an undiagnosed condition or a serious change in adrenal function. This is a medical emergency and potentially life-threatening situation. Hospitalization is often necessary part of this disease.
Symptoms of this are:
1.) Sudden pain in legs, lower back, or abdomen
2.) Severe vomiting and diarrhea
4.) Low blood pressure
5.) Syncope – Loss of consciousness or ability to stand
6.) Hypoglycemia [Low blood sugar]
10.) Slurred Speech
Treatment for Crisis
Standard therapy involves injections of hormones. Large volumes of IV fluid including Dextrose. Fluid by mouth is the next treatment when patient becomes more stable.
Take a look at this to get a better understanding:
Click on the picture to get a better view!
This question has been asked of me several times now. It is an interesting question, wouldn’t you say? The reason it is so intriguing is that it happens to almost all of us.
Therefore, one would think, it would be a genetic thing. And the answer is yes and no.
The estimate is that a normal person (whatever that really means anyways) has around 100,000 – 150,000 strands of hair on your head. That doesn’t take into account arm, back, leg, or genital hairs. The numbers could be twice that amount or more.
Hair cells, divide so often, that they can duplicate themselves in a few short hours. Some divide faster, that is why some hair grows quicker. As we get older, the cell division, for the most part, slows down. Only the cells of bone marrow grow quicker.
Hair is actually white pigments changing the color. There are two types of pigments – Dark (eumelanin) and light (phaeomelanin). These two pigments will blend together and create the individual hair color.
On a Genetic Level
Our genes are the basic code that determines our hair color. We will discuss a chemical called melanin that is closely related to hair color. But our genes are equally as important. Our genes from our parents give us our hair color. There are many aspects of genes involved that is why shades of color are important.
There isn’t a single gene for blond if so….that would mean only a few basic hair colors.
That would be so boring!!
Cell Growth of Hair
At the base of each hair is a hair follicle. This is the pigment of cells responsible for hair growth. Pigment cells are also what are responsible for the color of the hair. A chemical is produced called melanin. This substance is what is responsible for our hair color: red, black, blond, brown or another combination.
The amount, type, and mixture of melanin will lead to hair color.
This can occur at any age. Part of this may have to do with genetics. If your Dad or Mom went gray at twenty you are at risk of doing the same thing. Gray can come immediately or over time. Genetics and some other things play a role in this. Probably the most important role is genetics.
Your risk of going grey – on average – increase around 10-20% for every decade of life after 30.
Death of the Follicle
Over time, as we age, the pigment aspect of the follicle starts to die. It may not be all at once or all the follicles at once. This turns the color or the hair loses color. The result may be grey, white, silver, or some combination.
Other causes of a Grey color
Since Genes aren’t the only issue what are other things to consider. Well, where you live can play a huge role. A very dry climate can be harsh on the hair. It can lead or be a risk factor to color change. Just as when you were a kid, and played at the beach, and your color lightened a similar thing can happened.
Next, things like toxins, chemical exposure and pollutants all can affect hair color. These aren’t necessarily a short term thing. But for long exposure can be the culprit.
Stress, Children, and Medical Issues
There are many who would argue – despite chemical changes – stress and children can lead to grey hair.
Truthfully, the jury is still out on this. Obviously there are people we’ve seen that have dramatically changed their hair color – no of their own choosing.
But we can’t be certain – it wouldn’t have happened otherwise.
I see the proof in some photos of those who’ve had a difficult time. Some – but not all have had dramatic changes.
Therefore – stress has to be at least a consideration.
Gardasil is one of the few available vaccines for HPV.Â Â Human Papillomavirus or more commonly known as HPV is a virus that is sexually transmitted. It has several types, but only a few types have been directly linked to cervical cancer.
Recently the The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices voted and approved the use of Cervarix for girls 11 and 12.
Gardasil has been approved for use since 2006.
Cervarix was approved by the Food and Drug Administration on October 16th
The panel also voted to approved the use of Gardasil to males between the age of 9 through 26.
The dosing for Gardasil and Cervarix will be approved and allowedÂ in the Government’s Vaccines for Children program
This program will provide immunizations free for uninsured and under-insured children.
Dosing for both will be given in 3 doses
-Â Â Â 1st shot:
-Â Â Â 2nd shot:Â Â 1-2 months following the 1st shot
-Â Â Â 3rd shot:Â Â 6 months followingÂ 1st shot
Gardasil is made by Merck & Co
Cervarix is made by GlaxoSmithKline
Will Boys choose to have Vaccine?
This appears one of the main questions.Â Â Since men don’t get cervical cancer they may not feel the responsibility.Â Â Although the vaccinationÂ does not Â just cover cervical cancer but coversÂ genital warts as well.
It is believed that only 1% of sexually active males in the U.S. develop genital warts.Â Â Genital warts are not life threatening.
The true benefit would return back to the female.
Some argue to require or mandate a vaccination and prompt health insures to pay for this vaccination.
Currently no mandate has been put into place but the CDC will begin debating this argument in the next few weeks.
A Harvard University study recently placed in the British Medical Journal this mouth found no cost benefit by vaccinating boys. Consideration forÂ the benefit that women would gain was added into this study, though it didn’t change the outcome.Â Â However, Mereck didÂ their own study and found the results were different from the study done at Harvard University.
“It may seem unfair:Â Â Should this burden be borne by only girls and women?” asked Nancy Berlinger of the Hastings Center, a nonprofit bioethics research institute.
Check out the blog article entitled:Â HPV Vaccine may do more than prevent Cervical Cancer, it may cause girls to be more cautious about sexual activity