Also referred to as Allergic angiitis and granulomatosis

Is a median and small vessel inflammation of autoimmune origin

Typically seen in the vessels of the lungs

Can also be involved in the gastrointestinal system, heart, skin, kidneys and other organs.

Often seen in individuals with asthma

It is a rather rare disease

3 stages:

1.)   Affects sinuses and initial symptoms of allergies

2.)    Acute asthma    [that has not previously been seen in the individual]

3.)    Additional organs involvement

Treatment

Acute phase
•         Corticosteroids
•         Cyclophosphamide

Once in remission
•         Azathioprine
•         Methotrexate