Dysfunctional Uterine Bleeding or  [DUB] is the most common cause of abnormal vaginal bleeding for women.

It is considered an abnormal genital tract bleeding and is based in the uterus and is when there is an absence of structural or organic pathology.

Normal bleeding is menstruation that is seen for approximately 2-7 days – the cycle between menstruation is every 21-35 days.

Hormones involved in Dysfunctional Uterine bleeding  include:   Estrogen and Progesterone

There are several types of bleeding dysfunction

DUB is Classified into two types:

1.)  Ovulatory
2.)  Anovulatory


  • 10% of cases are ovulation
  • Abnormal bleeding occurs with relation to ovulation
  • May point to an endocrine involvement
  • Bleeding may occur mid or late cycle


  • 90% of cases are anovulatory
  • Abnormal bleeding without involvement to ovulation
  • Cause is often associated with rapid weight loss or weight gain, stress, exercise, drugs, or others.
  • Overall endocrine involvement relates to several hormones.


  • Hormone therapy – high dose of Estrogen and Progesterone
  • Though drug of choice is Progesterone.
  • Iron replacement for anemia
  • Hysterectomy is done in some cases
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