Hepatic Vein Obstruction is also referred to as Budd-Chiai Syndrome
Anatomic and physiologic changes are brought about by reduction of hepatic venous outflow.
Can see a blockage in the Hepatic Vein – this takes blood from the liver and returns it to the heart.
The result of this blockage is damage to the liver.
75% is associated with predisposing factors of hereditary and acquitted hypercoagulable states.
25% have multiple disorders
Causes my be a tumor or a thrombi (blood clot)
- Painful abdomen
- Enlarged spleen
- In a more chronic form varices and hepatic coma may be possible.
- Identifiable cause can not be found in every patient
- Thrombosis – primary cause (75%)
- Thrombosis (blood clot) found in hepatic vein
- Secondary (25%)
- Postpartum state
- Polycythemia Vera
- Oral Contraceptive use
- Liver Cancer
- Lupus anticoagulant
Doppler Ultrasound can be helpful
Liver biopsy when appropriate
*** Is dependent on cause
- Ascites – treat with fluid and salt retention and diuretic
- TIPS procedure placement in certain individuals
- Anticoagulation medication