membrane attack

Forms on the surface of a foreign or pathogenic cell

Is the result of the cascade of the Complement System.

Is an important aspect of the immune system

Composed of several proteins from the complement system:

     -    C5b
     -    C6
     -    C7
     -    C8
     -    C9

Forms a ring structure that attaches to the foreign cell.

Causes an opening or “punches a hole” into the outer cellular structure.

This pore causes a release of cellular components such as water, ions and small molecules from the foreign invaders

The result is lysis or death of the cell.

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