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Membrane Attack Complex forms on the surface of a foreign or pathogenic cell.

This is a direct result of the cascade of the Complement System and is an important aspect of the immune system

Composed of several proteins from the complement system:

–  C5b
–  C6
–  C7
–  C8
–  C9

1.)  Forms a ring structure that attaches to the foreign cell.

2.)  Causes an opening or “punches a hole” into the outer cellular structure.

3.)  This pore causes a release of cellular components such as water, ions and small molecules from the foreign invaders

4.)  The result is lysis or death of the cell.