fatty_liverNon-Alcoholic Fatty Liver Disease is a medical condition that affects the Liver but that occurs in patients with little, if any, alcohol use.

Alcohol is a large risk factor for liver disease, damage, fibosis.

When alcohol is the cause agent of liver disease it is referred to as Alcohol-Induced Liver Disease

Fatty liver may be present with and without Alcohol and this is referred to as Steatosis

Inflammation is another type or concern – this can lead to fibrosis.

Individuals can have no symptoms

Can lead to hepatic fibrosis, Cirrhosis, and mortality

Potential Causes 

  • Obesity (40%)
  • Diabetes Mellitus (20%)
  • Hypertriglyceridema (20%)  (Elevated Lipid profile)
  • Hypertension (High Blood pressure)
  • Poisons
  • and others

Symptoms:

  • Enlarged Liver (75%)
  • Fatigue
  • Weakness
  • Malaise
  • Weight loss
  • Loss of appetite
  • Nausea
  • Ascites
  • Jaundice

Diagnosis

  • Medical Exam and History
  • Abnormal blood work – especially Liver Enzymes
  • Liver biopsy may be appropriate
  • Ultrasound
  • CT may be benefical

Treatment:

  • Weight loss
  • Exercise

Medications

  • Metformin in diabetic individuals
  • Blood pressure mediations
  • High Lipid medications
  • Vitamin E
  • Vitamin C
  • Ursodiol (Actigall)  – may be helpful
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