Is a common disorder related to an endocrine disorder.

It affects approximately 5-10% of women

Often seen in women of reproductive age who are having abnormal or absent menstruation

Is the leading cause of Infertility

Other associated factors include diabetes diabetes, obesity, and insulin resistance

Abnormal LH (luteinizing hormone) levels relative to FSH (follicle-stimulating hormone) causes increased hormonal production by the theca cells of the ovaries.

Symptoms:
•     Facial hair (hirsutism) – 50% of cases
•     Abnormal or Absent menstruation – 50%
•     Obesity – 40%
•     Abnormal uterine bleeding – 30%
•     Development of male characteristics – 20%
•     Normal menstruation – 20%
•     Insulin Resistance
•     Increased risk for type II diabetes
•     Depression

Treatment includes:
   -    weight loss

If pregnancy is desired some improvements have been seen with the following:
   -    Clomiphene
   -    Dexamethasone or other drugs for ovulatory stimulation
   -    Metformin
   -    Rosiglitazone
   -    Pioglitazone

If pregnancy is not desired:
   -    Progesterone acetate

Management of excess hair:
   -    Dexamethasone
   -    Spironolactone
   -    Flutamide
   -    Finasteride

-     Hysterectomy if severe followed by hormone replacement