Portal Hypertension is a medical condition of Hypertension (High Blood Pressure) of the hepatic portal system.
It involves the relationship between portal venous blood flow and the resistance offered to the blood flow within the liver.
Can be defined where these is a Hepatic Venous Pressure Gradient equal or greater than 6 mmHg.
Cirrhosis from alcohol or chronic viral hepatitis is most common cause of portal hypertension, although there are other causes.
- Enlarged spleen
- and others
Most all causes circle around Liver changes (Hepatic).
Can be defined in 3 categories:
1.) Prehepatic Causes
2.) Hepatic Causes
3.) Posthepatic Causes
- Splenic Vein Thrombosis
- Portan Vein Thrombosis
- Viral Hepatitis
- Fatty Liver Disease
- Bilary Atresia
- Chronic Pancreatitis
- Primary Sclerosing Cholangitis
- hereditary Heemorrhagic Telangiectasia
- Congenital Hepatic Fibrosis
- Toxicity – from medications (Vitamin A, Azthioprine, Methotrexate, Amiodarone, and others)
- Toxicity – from Aresnic, Copper, and others
- Inferior Vena Cava Obstruction
- Right sided Heart failure
- Hepatic Vein Thrombosis
- Budd-Chiari Syndrome
- Testing the via HVPG (Hepatic Venous Pressure Gradient)
***Largely depends on cause
- Isosorbide mononitrate
Transjugular intrahepatic portosystemic shunting
Treatment for Asictes is often required.