This condition is when a loss of ovarian function occurs unexpectedly.
Is also called Ovarian Hypofunction
In this condition, abnormal loss of function occurs prior to the age of 40 – it becomes a medical concern.
If the ovaries fail, they are unable to produce eggs as well as the normal amounts of the hormone estrogen
This can lead to Infertility and other problems.
The lack of estrogen can be problematic when not treated.
Normally, the function of the ovaries continue through menopause and typically ends in the early to mid 50′s.
3 main findings:
1.) Amenorrhea
2.) Hypergonadotropinism
3.) Hypoestrogenism
Additional Symptoms:
- Vaginal dryness
- Vaginal itching
- Hot flashes
- Decrease bone mass
- Decreased sexual activity
Causes:
- Unknown or Idiopathic
- Autoimmune
- Turner syndrome
- Chemotherapy therapy
- Radiation therapy
The most noted complication of POF is Infertility – this occurance is not 100% as a small portion of individuals will suddenly become pregnant.
Additional complications include:
- Osteoporosis
- Decreased bone density
Increased risks
- Hypothyroidism
- Addison’s disease
- Hashimoto’s Disease
- Heart disease
Treatment and Management
No fertilty treatment has been effective at this point in time
Adoption and In-Vito Fertilization are options
*** – caution for those individuals
. who smoke and are over the age or 35
. history of thrombus events
. uncontrolled hypertension
. diabetes mellitus