
Referred to as granulomatous inflammation of the lungs
Is an immune system disorder whose cause is relatively unkown.
Typically individuals exhibit symptoms in there 30s and 40s
World wide incidence is anywhere from 1 to 40 per 100,000
Most often seen in Northern European Countries such as Sweden and Iceland
North American Blacks and Northern European Whites have a higher incidence
Women are affected more than men
Symptoms
- Variety of symptoms can be seen
- Seen in several organs such as lungs, kidney, skin, liver, nerves, heart, eyes or others.
- Fatigue
- Fever
- Shortness of breath
- Cough
- Joint pain
X-rays are important and can be helpful
Biopsy is essential for diagnosis with a finding of granulomatous inflammation
Treatment
· Oral corticosteroids
- prednisone
. Long term control may be indicated
· Severe condition may require imunosuppressant:
- azathioprine
- methotrexate
