Singuliar, also known as Montelukast, is a Leukotriene Receptor Antagonist  (LTRA) that has a primary use in Asthma

It is important to take this medication at the same time every day.

Use:

  • It’s primary use is for the treatment of Asthma
  • It also can help relieve symptoms of seasonal allergies, bronchospasms, allergic rhinitis, and urticaria.
  • It is not used in treatment of Acute Asthma attacks.  (An inhaler will be used in these cases)

Dosing

  • Montelukast comes as a tablet, a chewable tablet, and granules to take by mouth.
  • It is usually taken once a day with or without food.
  • If you are giving the granules to your child, you should not open the foil pouch until your child is ready to take the medication

There are several ways that you can give the granules to your child.

1.)  Pour all of the granules directly from the packet into your child’s mouth to be swallowed immediately.

2.)  Pour the entire packet of granules onto a clean spoon and place into mouth.

3.)  Mix the entire packet of granules in 1 teaspoon baby formula, breast milk, applesauce, soft carrots, ice cream, or rice.

* other food items or liquids are not recommended.

 

Dosing by Age group

For Adults and Adolescents 15 years of age and older: One 10-mg chewable tablet.
For pediatric patients 6 to 14 years of age: One 5-mg chewable tablet.
For pediatric patients 2 to 5 years of age: One 4-mg chewable tablet or one packet of 4-mg oral granules.
For pediatric patients 12 to 23 months of age: One packet of 4-mg oral granules.
Safety and effectiveness in pediatric patients less than 12 months of age with asthma have not been established.

 

Method of Action

  • It is a a CysLT antagonsist which blocks the action of Leukotriene D4.
  • This is located in the lungs.
  • When this occurs, less bronchoconstriction and thus less inflammation of the lungs occurs.

Adverse Effects

  • Gastrointestinal problems
  • Headaches
  • Allergic Reactions  (Swelling of face, arms, hands, others)
  • Problems with sleeping
  • Rash
  • Itching

Patent

  • The patient for Singulair expired on August 3rd 2012.
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