Sulfonylurea is a group of medications that are primarily used to treat Diabetes Mellitus Type 2.

Action:

  • Increases the amount of insulin that is released in the Pancreas
  • Insulin is secreted by beta cells in pancreas

Types:

First Generation

  • Acetohexamide
  • Chlorpropamide
  • Tolbutamide
  • Tolazamide

Second Generation

  • Glipizide
  • Gliclazide
  • Glibenclamide  [Glyburide]
  • Gliquidone
  • Glyclopyramide

Third Generation

  • Glimepiride

Uses:

1.) Diabetes Mellitus Type 2

  • Are often used alone or with another medication.

Side Effects:

  • Hypoglycemia
  • Weight gain
  • Headache
  • Nausea
  • Diarrhea
  • Abdominal discomfort

***- are not to be used during pregnancy or in someone who may become pregnant.

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