Thiazolidinediones (TZDs) is a group of medications that are used treat Diabetes Type 2.

This medication was introduced in the late 1990s.

Actions:

  • Decreases the “resistance” of insulin

Different Medictions

  • Rosiglitazine  (Avandia)
  • Pioglitazone  (Actos)
  • Troglitazone (Rezulin) – this is no longer on market due to drug-induced hepatitis

 

Use:

1.)  Diabetes Mellitus Type 2

Side Effects

  • Water retention
  • Weight gain
  • Others
  • Possible liver failure when stopping troglitazone only – other medications have not been showed to have this side effect
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