Thiazolidinediones (TZDs) is a group of medications that are used treat Diabetes Type 2.
This medication was introduced in the late 1990s.
- Decreases the “resistance” of insulin
- Rosiglitazine (Avandia)
- Pioglitazone (Actos)
- Troglitazone (Rezulin) – this is no longer on market due to drug-induced hepatitis
1.) Diabetes Mellitus Type 2
- Water retention
- Weight gain
- Possible liver failure when stopping troglitazone only – other medications have not been showed to have this side effect